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Brenda C Crews Selected Research

Neoplasms (Cancer)

1/2022Discovery of a Redox-Activatable Chemical Probe for Detection of Cyclooxygenase-2 in Cells and Animals.
11/2016Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors.
11/2016Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis.
6/2016Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer.
5/2015Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe.
1/2015Conjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance.
11/2014Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors.
6/2014PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.
6/2014Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance.
4/2014Trifluoromethyl fluorocoxib a detects cyclooxygenase-2 expression in inflammatory tissues and human tumor xenografts.
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Brenda C Crews Research Topics

Disease

14Neoplasms (Cancer)
01/2022 - 04/2006
8Inflammation (Inflammations)
10/2020 - 04/2006
3Ovarian Neoplasms (Ovarian Cancer)
10/2020 - 06/2014
3Squamous Cell Carcinoma of Head and Neck
06/2016 - 05/2013
3Carcinogenesis
01/2015 - 03/2012
2Adenocarcinoma
10/2020 - 11/2016
2Colonic Neoplasms (Colon Cancer)
11/2016 - 07/2007
1Carcinoma (Carcinomatosis)
10/2020
1Pain (Aches)
10/2020
1Anxiety Disorders (Anxiety Disorder)
10/2020
1Osteoarthritis
10/2020
1Neoplasm Metastasis (Metastasis)
11/2016
1Adenocarcinoma of Lung
11/2016
1Choroidal Neovascularization
01/2016
1Macular Degeneration (Age-Related Maculopathy)
01/2016
1Retinal Diseases
01/2016
1Vascular Diseases (Vascular Disease)
01/2016
1Ovarian Epithelial Carcinoma
06/2014
1Edema (Dropsy)
05/2013
1Neuroinflammatory Diseases
03/2012
1Breast Neoplasms (Breast Cancer)
01/2012
1Atherosclerosis
08/2005

Drug/Important Bio-Agent (IBA)

9Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2022 - 05/2010
5EnzymesIBA
10/2020 - 04/2014
5Biomarkers (Surrogate Marker)IBA
06/2016 - 04/2006
3CarrageenanIBA
10/2020 - 05/2013
3Cyclooxygenase 1IBA
10/2020 - 06/2014
3Proteins (Proteins, Gene)FDA Link
11/2016 - 04/2013
3Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
11/2016 - 08/2005
3fluorocoxib AIBA
06/2016 - 04/2014
3Indomethacin (Indometacin)FDA LinkGeneric
05/2013 - 07/2007
2Celecoxib (Celebrex)FDA Link
05/2015 - 02/2011
2PlatinumIBA
01/2015 - 06/2014
2Indicators and Reagents (Reagents)IBA
04/2013 - 05/2010
1indoleIBA
10/2020
1Cytidine Monophosphate (CMP)IBA
10/2020
1EndocannabinoidsIBA
10/2020
1RadiopharmaceuticalsIBA
05/2019
1Dinoprostone (PGE2)FDA Link
11/2016
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2016
1Retinaldehyde (Retinal)IBA
01/2016
1Antineoplastic Agents (Antineoplastics)IBA
01/2015
1FluorineIBA
11/2014
1Cisplatin (Platino)FDA LinkGeneric
06/2014
1Coloring Agents (Dyes)IBA
04/2013
1RhodaminesIBA
04/2013
1azuleneIBA
01/2012
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
10/2011
1Contrast MediaIBA
05/2010
1PPAR gammaIBA
07/2007
1sulindac sulfideIBA
07/2007
1indomethacin phenethylamideIBA
08/2005
1LDL Receptors (LDL Receptor)IBA
08/2005
1Apolipoproteins E (ApoE)IBA
08/2005

Therapy/Procedure

2Therapeutics
06/2014 - 10/2011
1Lasers (Laser)
01/2016
1Analgesia
03/2012
1Drug Therapy (Chemotherapy)
04/2006